Robust asymmetric synthesis of unnatural alkenyl amino acids for conformationally constrained α-helix peptides.
نویسندگان
چکیده
The efficient asymmetric synthesis of unnatural alkenyl amino acids required for peptide 'stapling' has been achieved using alkylation of a fluorine-modified Ni(II) Schiff base complex as the key step.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 43 شماره
صفحات -
تاریخ انتشار 2014